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Explore how our devices are transforming the treatment of sexual dysfunction across key areas of women's & men's health. Evidence-based outcomes, backed by science, shaped by data & grounded in clinical rigor. Since the beginning of this decade, our devices have been at the forefront of independent clinical research across the US, UK & Europe. All studies are designed, conducted & published by leading urologists, Ob- Gyns, pelvic floor therapists & sexual health researchers, completely independently to ensure objectivity & deliver the highest scientific standards.
With 15 studies completed & dozens more underway, we’re continually deepening our understanding of where our devices are most effective, how they can be improved, and what innovations are needed next. This ongoing research spans a wide spectrum of sexual health challenges - from erectile dysfunction, prostatitis, and pelvic pain to arousal, dryness, orgasmic disorders, and more.
What follows is a growing body of clinical evidence-led by experts, published in respected journals, and proven in practice. It’s how we turn medical innovation into trusted, therapeutic impact. Doctor-led studies. Peer-reviewed Journal Publications. Real-world results.
Numerous clinical trials have demonstrated the strong efficacy of Crescendo 2, Poco, Legato & Molto in treating conditions like genito-pelvic pain, arousal & lubrication disorders, anorgasmia and vaginismus.
Led by clinicians, these studies have shown 2X to 5X improvements in FSFI domains of pain, lubrication & orgasm, with no adverse effects, establishing these devices as safe, effective & clinically significant interventions in modern sexual medicine.
Genito-Pelvic Pain Penetration Disorders (GPPPD), a common but challenging sexual pain condition in women.
Over 12 weeks, patients experienced a 5X improvement in sexual pain scores (FSFI domain increased significantly from 0.40 to 2.32). The treatment demonstrated effectiveness and safety, with no adverse effects reported, suggesting Crescendo as an important therapeutic option for managing GPPPD. (LINK)
Researchers assessed the effectiveness of combining Cognitive Behavioral Therapy (CBT) with the Crescendo device for treating Female Sexual Arousal Disorders (FSAD), aiming to boost sexual arousal and lubrication.
After 12 weeks, patients showed a 73% improvement in FSFI Arousal scores and a remarkable 93% improvement in Lubrication scores. The combination therapy significantly improved both domains with no adverse effects, highlighting Crescendo and CBT as a powerful therapeutic duo. (LINK)
This prospective case series assessed Crescendo 2’s effectiveness for women experiencing situational anorgasmia, characterized by difficulty achieving orgasm during sexual intercourse.
Within 6 weeks, participants reported a 2X improvement in orgasmic function (FSFI orgasm scores from 1.62 to 3.47) and a 90.47% success rate achieving orgasm during intercourse. Crescendo 2 was effective, safe, and also reduced the overall duration and cost of treatment. (LINK)
This study assessed Crescendo II, a flexible vibrating device, for improving sexual function, specifically orgasm, lubrication, and arousal - in women experiencing sexual dysfunction, including difficulties achieving orgasm during intercourse.
Patients showed significant improvement in FSFI orgasmic domain scores (scores increased from 1.62 to approximately 3.47 after 6 and 12 weeks) and achieved an impressive coital orgasm success rate of 90.47%. Additionally, lubrication and arousal significantly improved, emphasizing Crescendo II's safety and effectiveness.
Researchers investigated Legato, a device employing focused mechanical vibration (FMV), for women experiencing sexual arousal and lubrication issues.
After 8 weeks, women achieved an 83% improvement in FSFI Arousal scores and a remarkable 4X improvement in Lubrication. Legato effectively enhanced arousal and lubrication when used during intercourse, demonstrating substantial clinical promise for managing female sexual dysfunction. (LINK)
This case report explored an innovative therapeutic approach using Molto, a flexible vibratory device, to treat vaginismus, a condition causing severe genital pain during penetration.
Over an 8-week protocol, the patient experienced a significant 5X improvement in FSFI pain scores (from 0 to 4.8 on a 0-6 scale), and comfortably achieved intercourse. This individualized therapeutic approach using Molto provides a promising, accessible alternative to traditional vaginismus treatments. (LINK)
Numerous clinical trials with Tenuto 2, Tenuto Mini & Molto have shown significant improvements in erectile function, ejaculation & prostate health.
Across diverse patient populations such as those with psychogenic ED, post-prostatectomy dysfunction & chronic prostatitis, patients experienced 2X to 2.7X improvements in IIEF-5 scores, along with notable gains in sexual satisfaction and partner intimacy.
This clinical case explored using focal muscle vibrations (FMV) via Tenuto to manage neurogenic Erectile Dysfunction (ED) following colorectal cancer surgery, focusing on reducing muscular spasticity to enhance erectile function.
Within just 5 weeks, the patient experienced a 2X improvement in erectile function (IIEF-5 score from 7 to 15). Results indicated FMV through Tenuto effectively improved erectile function by managing spasticity and improving muscle synergy, suggesting strong therapeutic potential. (LINK)
The study examined Tenuto 2, an on-demand focused vibration device, for men with psychogenic Erectile Dysfunction (pED), a condition often challenging to treat with traditional methods.
Participants saw an impressive 81% improvement in erectile function over 8 weeks, demonstrating Tenuto 2’s potential as a safe and effective therapeutic alternative for treating psychogenic ED, especially when medications or counseling alone fall short. (LINK)
This clinical case evaluated Tenuto 2’s effectiveness using focused muscle vibration (FMV) therapy in managing erectile dysfunction following radiotherapy for prostate cancer, particularly for patients who had not responded to standard ED treatments.
Within just 5 weeks, erectile function improved by 2.3X (IIEF-5 score from 6 to 14), highlighting FMV via Tenuto 2 as an effective second-line therapy for post-radiotherapy ED, offering meaningful clinical improvement where other treatments had failed. (LINK)
This research explored the use of Tenuto 2, a wearable vibrating device, for improving erectile function during rehabilitation following radical prostatectomy - a surgical treatment for prostate cancer often resulting in significant erectile dysfunction.
After 6 months, participants showed notable recovery, with erectile function scores (IIEF) significantly improving (from an average of 11 pre-treatment to 19 post-treatment). Patients preferred Tenuto 2 to traditional rehabilitation methods, reporting enhanced intimacy, ease of use, and partner communication during their recovery period.
This case demonstrated the clinical utility of Tenuto Mini, a constriction vibration ring using focused mechanical vibration (FMV), for situational, non-organic erectile dysfunction - especially valuable when traditional couple-based therapies were not applicable.
Within 2 months, the patient’s erectile function improved by 2.7X (IIEF-5 scores from 6 to 16), showcasing Tenuto Mini’s ability to effectively manage ED independently, providing a viable therapeutic solution without medications or extensive therapies. (LINK)
The safety and preliminary effectiveness of Tenuto Mini, a vibrating constriction ring, were evaluated in men with psychogenic Erectile Dysfunction (pED).
Patients experienced a substantial 79% improvement in erectile function (IIEF-5 scores increased from 10.95 to 19.56) after 8 weeks. The device's unique combination of constriction and FMV proved highly effective, especially for patients unable or unwilling to pursue medications or therapy involving a partner. (LINK)
This study evaluated the effectiveness of Tenuto Mini, for men diagnosed with psychogenic erectile dysfunction (pED). The study enrolled 30 men (mean age ~39) over an 8-week period.
Patients experienced a significant improvement in erectile function, with IIEF-5 scores increasing from 14.44 to 22.31 (p < 0.001), and reported high treatment satisfaction (mean EDITS score: 78.57%) with no adverse effects were reported. (LINK)
This study investigated Molto, a malleable vibrating device designed to manage refractory chronic non-bacterial prostatitis - a condition notoriously challenging to treat due to persistent pain and sexual dysfunction.
After 3 months of device use, participants showed substantial pain relief (pain scores decreased significantly from 7/10 to 3/10) along with notable improvements in erectile function and sexual satisfaction. Patients found Molto easy to apply, reporting no adverse events, highlighting its promising therapeutic potential.
Researchers evaluated the effectiveness and tolerability of Molto, an anal insert device, in managing delayed ejaculation or anejaculation, conditions with limited and inconsistent treatment options.
Nearly half (45.5%) of the patients who completed the study successfully resolved their ejaculation issues within an average of 4 weeks of treatment. The device demonstrated good safety, comfort, and tolerability, representing a meaningful advancement in managing these challenging ejaculatory disorders.
This comprehensive overview discussed various sexual enhancement devices and their emerging evidence-based roles in clinical sexual medicine, aiming to bridge the gap between therapeutic utility and traditional perceptions of such devices. MV devices including Molto, Tenuto, Crescendo, and Legato, were highlighted as clinically relevant devices that not only enhance sexual pleasure but also provide measurable medical benefits. This acknowledgment reinforces the expanding role of such tools within evidence-based sexual health interventions. (LINK)
